ABSTRACT
BACKGROUND: In this case report, we presented a rare case of maternal death with massive vulvar edema and Covid-19 diagnosis. CASE PRESENTATION: The case was a 20-year-old woman who was referred to with pain and massive vulvar edema by passing 7 days from her labor. The laboratory tests showed leukocytosis, lymphopenia, and elevated C-reactive protein levels. The high-resolution computed tomography was in favor of Covid-19 changes. Finally, she died because of respiratory distress, ON the 8th day postpartum. CONCLUSION: Given the increasing prevalence of Covid-19, it is important and vital to be aware of its potential complications and then to try prevent and manage them, especially during high-risk periods such as pregnancy and postpartum.
Subject(s)
COVID-19/complications , Edema/complications , Edema/diagnostic imaging , Maternal Death , Postpartum Period , SARS-CoV-2/genetics , Vulvar Diseases/complications , Vulvar Diseases/diagnostic imaging , COVID-19/blood , COVID-19/virology , COVID-19 Testing/methods , Fatal Outcome , Female , Humans , Lymphopenia , Pregnancy , Reverse Transcriptase Polymerase Chain Reaction , Tomography, X-Ray Computed/methods , Young AdultSubject(s)
COVID-19/complications , Edema/complications , Hand/blood supply , Pain/etiology , SARS-CoV-2 , Venous Thrombosis/complications , COVID-19/epidemiology , Edema/diagnosis , Female , Humans , Middle Aged , Pain/diagnosis , Pandemics , Thrombectomy/methods , Ultrasonography, Doppler, Color , Venous Thrombosis/diagnosis , Venous Thrombosis/surgeryABSTRACT
Severe acute respiratory syndrome corona virus 2(SARS-CoV-2), the cause of coronavirus disease- 2019 (COVID-19) after emerging in china in late 2019 is spreading rapidly across the world. The most common cause of death in patient with COVID-19 is the rapid progression of acute respiratory distress syndrome (ARDS) shortly after the beginning of dyspnea and hypoxemia. Patients with severe COVID-19 may also develop acute cardiac, kidney and liver injury that are associated with poor prognosis and can lead to high mortality rate. Numerous randomized trials are ongoing to find an effective, safe and widely available treatment. Remdisivir is the only FDA -approved antiviral agent for treatment of severe COVID-19. Glucocorticoids (GCs) have been used for treatment of cytokine storm syndrome and respiratory failure in hospitalized patient with severe covid-19. One of the therapeutic effects of GCs is stability of vascular endothelial barrier and decreasing tissue edema. In our opinion, the decreasing vascular permeability effect of glucocorticoids in the injured myocardium might has an important additional factor in reducing mortality in severe, hospitalized COVID-19 patients.